PRO (yes)
O’Shaughnessy’s, a scientific journal, published a study in its Autumn 2005 issue titled “Cannabis Alleviates Symptoms of Crohn’s Disease,” by Jeff Hergenrather, MD, that found:
“[Crohn’s] patients described marked
improvements with the use of cannabis.

Beneficial effects
were reported for appetite, pain, nausea, vomiting, fatigue,
activity, and depression. Patients also reported that
cannabis use resulted in weight gain, fewer stools per day and
fewer flare-ups of less severity…

Cannabis-using Crohn’s patients not only
report significant relief of their symptoms, they are
also able to reduce the amount of
immunosuppressive medications that have been a mainstay of conventional

Crohn’s disease is so debilitating and
life-threatening and so difficult to manage with conventional
medications it is very encouraging to find that cannabis is
proving to be an effective treatment for it right

Autumn 2005 – O’Shaughnessy’s 

The Journal of Clinical Investigation published an article in Apr. 2004 by F. Massa, et al., from the Max Planck Institute of Psychiatry in Munich, titled “The Endogenous Cannabinoid System Protects Against Colonic Inflammation,” that stated:
“The major active constitutent of the
Cannabis sativa (marijuana),
THC, and a variety of natural
and synthetic cannabinoids have been shown to possess…
anti-inflammatory activities…

Results indicate
that the endogenous cannabinoid system represents a promising
therapeutic target for the treatment of intestinal disease
conditions characterized by excessive inflammatory

Apr. 2004 – Journal of Clinical Investigation 

Gut, a peer-reviewed medical journal, published a June 2001 reviewntitled “Cannabinoids and the Gastrointestinal Tract” by R. Pertwee, PhD, that found:
“Cannabinoid receptor agonists delay gastric
emptying in humans as well as in rodents, and they may also
inhibit human gastric acid secretion.

It is also worth
noting that there have been a number of anecdotal accounts of the
effective use of cannabis in the past against dysentery and

June 2001 – Gut 

Cell and Tissue Research published an article in Oct. 2000 titled “Localization of CB1-Cannabinoid Receptor Immunoreactivity in the Porcine Enteric Nervous System” by A. Kulkarni-Narla et al., that observed:
“Cannabis has been used for centuries in the
medicinal treatment of gastrointestinal disorders.

Oct. 2000 – Cell and Tissue Research  

The United Kingdom Parliament’s 1998 “Science and Technology-Ninth Report” noted:
“Dr. Anita Holdcroft of Hammersmith
Hospital…has reported the results of a placebo-controlled trial
of cannabis in a patient with severe chronic pain of
gastrointestinal origin…

The patient’s demand for morphine was
substantially lower during treatment with cannabis than during a
period of placebo treatment.”

1998 – United Kingdom Parliament