Sometimes you have to listen to your gut.
Gut Smart Research
What’s in the water at Northport?
Feb 6th
It is widely believed that Crohn’s disease and ulcerative colitis are autoimmune diseases causing inflammatory immune responses that damage the digestive system.
One alternative theory is that IBDs are not autoimmune diseases but immune deficiency diseases caused by a bacteria called Mycobacterium avium paratuberculosis (MAP). MAP prevents the immune system from properly ridding the body of it.
When reading the below story, which makes absolutely no mention of MAP, I couldn’t help by think it might play a part. I read a paper by John Hermon-Taylor a couple years ago and it says that MAP is commonly found in milk and the Red River up in Winnipeg. I had swam in the river as a teenager and 4 months later my symptoms of Crohn’s disease started.
Could something similar be happening to the people of Northport, WA? I hope to ask around and see what the people there think.
Study tracks reasons behind high rate of illness near Northport
Gail Leaden was 5 when she was diagnosed with ulcerative colitis. In high school, Leaden’s best friend in the small town of Northport, Wash., was diagnosed with the same illness.
“It’s not a common disease to begin with,” said Leaden, 25, who now lives in Spokane. “How ironic that my best friend gets it.”
Two doctors from Boston’s Massachusetts General Hospital are looking into reports of high rates of bowel disease in Northport, a town of 330 near the Canadian border. In the general population, about 4 people per thousand are diagnosed with Crohn’s or colitis.
“We should be expecting to see one or two cases for a town the size of Northport,” said Dr. Sharyle Fowler, who will be working on the study.
The disease cluster, if it can be confirmed, could shed light on triggers for Crohn’s disease and ulcerative colitis, said Dr. Josh Korzenik, director of Massachusetts General’s Crohn’s and Colitis Center. No one knows what causes the diseases, which affect 1.5 million Americans, but both appear to have genetic and environmental contributors.
“We were drawn to this because it’s an unusual cluster, or potential cluster, in a small population,” Korzenik said.
Rates of Crohn’s disease and colitis are on the upswing in industrialized countries.
About 320 current and former Northport residents provided health information. Thirty-six said they had ulcerative colitis; 18 said they had Crohn’s disease.
Jamie Paparich suspects a link to the smelter. Her grandparents raised six children on a farm outside of Northport, about 15 miles downwind and downstream of the smelter owned by Teck Resources Ltd. For decades, the century-old smelter released tons of pollution daily into the air and the Columbia River, including mercury and other heavy metals.
Both her dad and her aunt, who grew up on the farm, were diagnosed with ulcerative colitis. They ate vegetables from the family’s garden and swam in the Columbia River.
The families “weren’t related by any stretch, yet we all had these same problems,” said Kalamarides
Deane said the smelter has cleaned up its act. In 1995, the smelter stopped dumping slag, a byproduct of the smelting process, into the Columbia River. Slag contains 25 compounds, including heavy metals. The smelter also halted production of phosphate fertilizer, reducing mercury releases into the river.
Northport resident Barb Anderson thinks the community needs answers.
At Rockwood Clinic in Spokane, where the diagnosis was made, doctors were surprised that two of Kelsey’s classmates had the same illness, said Barb Anderson. Leaden also remains troubled by the coincidence. It makes her suspect “that something’s not right.”
Pharma Funded Study Says Their Antibiotics Help with IBS[06Jan11]
Jan 6th
The practice of pharmaceuticals funding for studies on their own drugs is stupid. There’s no way in hell I’m going to trust this antibiotic really helps. The doc even admits the results are in the lower spectrum of clinically relevant. Data can be easily manipulated to be more favorable than it really is.
The use of antibiotics is boarding on ludicrous levels. It’s in our soaps, in our food and in our bodies.
Two weeks of treatment with an already well-known antibiotic appears to offer relief to those suffering from at least one type of irritable bowl syndrome, new research finds.
IBS is a common gastrointestinal ailment that’s marked by abdominal pain, severe bloating, diarrhea or constipation, or both. Treatments for the condition are few and usually involve dietary and lifestyle changes.
Two industry-funded studies, published in the New England Journal of Medicine, looked at patients with diarrhea-predominant IBS — a form that only a minority of IBS patients have.
A total of 1,200 patients took either 550 milligrams of rifaximin or placebo pills, three times a day, for two weeks. Overall, 41 per cent of patients on rifaximin reported “adequate relief” for at least two weeks, compared to 32 per cent on dummy pills.
The treated patients said they had less bloating and abdominal pain, and improved stool consistency. The benefits lasted for the 10 weeks they were followed.
In an accompanying editorial, Dr. Jan Tack of the University of Leuven in Belgium, noted that the difference between the treated and the untreated groups was “in the lower spectrum of what is considered to be clinically relevant.” But the results were nonetheless notable.
The study was designed and funded by rifaximin’s maker, Salix Pharmaceuticals Inc. — a fact disclosed by the researchers.
Salix, which markets rifaximin as a treatment for traveller’s diarrhea under the name Xifaxan in the U.S., is seeking to expand the drug’s use to IBS. A decision from the Food and Drug Administration is expected in March.
Tack urged doctors to proceed with caution until more research is done on rifaximin in IBS.
He notes that with the high prevalence of IBS – as many as one in five Americans and Canadians are thought to suffer from the condition – there are worries about how the large-scale use of poorly absorbed antibiotics would have on antibiotic-resistance.
For that reason, he urges the antibiotic be restricted to those who haven’t responded to other IBS treatments.
Empowerment Leads to Greater Healing? [26Dec10]
Dec 26th
The mind cannot be discounted as playing a vital role in our ability to heal from illness.
Placebos Work — Even if Patients Are in on the Secret
Confronting the “ethically questionable” practice of prescribing placebos to patients who are unaware they are taking dummy pills, researchers found that a group that was told their medication was fake still reported significant symptom relief.
In a study of 80 patients with irritable bowel syndrome (IBS), a control group received no treatment while the other group was informed their twice-daily pill regimen were placebos. After three weeks, nearly double the number of those treated with dummy pills reported adequate symptom relief compared to the control group.
Those taking the placebos also doubled their rates of improvement to an almost equivalent level of the effects of the most powerful IBS medications, said lead researcher Dr. Ted Kaptchuk, an associate professor of medicine at Harvard Medical School and Beth Israel Deaconess Medical Center.
Multiple studies have shown placebos work for certain patients, and the power of positive thinking has been credited with the so-called “placebo effect.”
Prior to their random assignment to the placebo or control group, all patients were told that the placebo pills contained no actual medication. Not only were the placebos described truthfully as inactive pills similar to sugar pills, but the bottle they came in was labeled “Placebo.” Health care providers also spent about 15 minutes explaining how placebos can have powerful effects and that a positive attitude, while not essential, could help.
At the end of the study, which was funded by the National Center for Complementary and Alternative Medicine and the Bernard Osher Foundation, 59 percent of the women in the placebo group reported adequate symptoms relief, vs. 35 percent of the control group.
“Some patients were very disbelieving, some were very enthusiastic, but by the end many really enjoyed themselves,” Kaptchuk said. “They felt empowered.”
He theorized that the very ritual of taking pills to treat illness — even fake ones — initiates a brain response that changes the way patients perceive and experience their symptoms.
“There’s nothing that’s not in our heads,” Kaptchuk said. “Our emotions, sadness, anxiety, all interact with our symptoms.”
Does MAP Bacteria Cause IBD? [18Dec10]
Dec 18th
This debate of whether MAP causes IBD has been raging in the medical community for 30 years. I think there’s a strong possibility that it is true.
Mycobacterium avium, subspecies paratuberculosis (MAP) causes a chronic granulomatous disease of the intestines in dairy cows and a wide range of other animals, including nonhuman primates, called Johne’s (“Yo-knee’s”) disease. MAP has been consistently identified by a variety of techniques in humans with Crohn’s disease.
The research investigating the presence of MAP in patients with Crohn’s disease has often identified MAP in the “negative”ulcerative colitis controls as well, suggesting that ulcerative colitis is also caused by MAP.
The apparently opposite role of smoking, increasing the risk of Crohn’s disease but decreasing the risk of ulcerative colitis, is explained by a more careful review of the literature that reveals smoking causes an increase in both diseases but switches the phenotype from ulcerative colitis to Crohn’s disease.
MAP as the sole etiologic agent of both ulcerative colitis and Crohn’s disease explains their common epidemiology, geographic distribution and familial and sporadic clusters, providing a unified hypothesis for the prevention and cure of the no longer “idiopathic”inflammatory bowel diseases.
Author: Ellen Pierce
Credits/Source: Gut Pathogens 2010, 2:21
SAD can lead to IBD [12Dec10]
Dec 12th
I wonder if the patients were eating a lot of processed foods. I believe the processed foods kill off probiotics that help keep our gut in good health.
A diet high in fats and protein increases the risk of developing ulcerative colitis and Crohn’s disease, researchers found.
The studies consistently showed that high dietary intake of total fats, polyunsaturated fatty acids, omega-6 fatty acids, and meat is associated with an increased risk of Crohn’s disease and ulcerative colitis.
In contrast, high fiber and fruit intake decreases the risk of Crohn’s disease and high vegetable intake reduces the risk of ulcerative colitis
The investigators theorized that the increasing popularity of a “western” diet throughout the world may be responsible for the rising incidence of IBD.
REFERENCE:
1. Hou J, Abraham B, El-Serag H. Diet and risk of development of inflammatory bowel disease: a systematic review. Paper presented at: 2010 Advances in Inflammatory Bowel Diseases Conference; December 9-12, 2010; Hollywood, Florida.
For the Good of the Gut – Can Parasitic Worms Treat Autoimmune Diseases? [01Dec10]
Dec 5th
Should You Trust BigPharma with Your Health? [12Nov10]
Nov 12th
My answer?
A resounding “NO!”
Physician William D. Leak was found to have performed unnecessary nerve tests and excessive invasive procedures, including injecting some patients with agents that destroy nerve tissue. But that didn’t stop Eli Lilly from using him as a promotional speaker and adviser.
Leak is part of the drug industry’s sales force of doctors who are paid to promote brand-name drugs to their peers. Drug companies claim they hire the most-respected doctors in their fields for this purpose.
But an investigation has uncovered hundreds of doctors on company payrolls who have been accused of professional misconduct or lacked credentials as researchers or specialists.
But as an analysis by ProPublica found, drug companies are not always hiring “experts” to act as spokespeople. Instead, they’re often hiring the bottom of the barrel, so to speak, including physicians who have some concerning pasts.
ProPublica has put together a comprehensive database that reveals just how much drug companies are paying doctors, and you can even search for your own doctor to find out if he or she is being paid by the industry.
They compiled data from seven drug companies, including nearly $258 million in physician payouts since 2009, and found some revealing data about the paid speakers and consultants.
- Sanctions against more than 250 speakers
- Some of the doctors had lost their licenses
- More than 40 have received FDA warnings for research misconduct, lost hospital privileges or been convicted of crimes
The idea that drug companies are recruiting only top experts and consummate professionals to do their promotions is a myth. In some cases, there are reputable physicians on their payroll, but many of the most prestigious universities, including Harvard, are now banning their staff from receiving money from drug companies for speaking.
Instead, industry whistleblowers have alleged that drug companies choose their speakers, as ProPublica reported, “on their prescription potential rather than their true credentials.”
Sociologist Susan Chimonas, who researches doctor-pharma relationships, told ProPublica:
“It’s sort of like American Idol … Nobody will have necessarily heard of you before — but after you’ve been around the country speaking 100 times a year, people will begin to know your name and think, ‘This guy is important.’ It creates an opinion leader who wasn’t necessarily an expert before.”
So the physicians being paid to counsel your physician — who in turn may influence the drugs you end up taking — are not only biased in favor of the drug company that is paying them a substantial fee, they may be vastly underqualified as well.
They attack the market on multiple levels. For instance, many of the articles that appear in medical journals purportedly written by well-known academics are actually written by unacknowledged ghostwriters on Big Pharma payroll.
Drug companies also employ an army of reps who often give gifts to convince doctors to prescribe the medications that they represent. These drug reps usually have no medical or science education. What they do have, however, is training in tactics that are on par with some of the most potent brainwashing techniques used throughout the world.
Worse yet, drug companies have compiled hit lists of doctors to be “neutralized” or discredited because they were speaking out against certain drugs.
Pharmaceutical companies actually spend almost twice as much on marketing than research, and this is how they are able to keep their medications front and center in your physician’s, and possibly your, mind.
So please remember first and foremost that drug companies are nearly always trying to sell you something that there are better natural solutions for. And your physician, too, if he or she is intertwined in the conventional medical field, may be inappropriately advising you to take drugs when better options exist.
Antibiotic Induces Remission of Crohn’s Disease[04Nov10]
Nov 3rd
It’s great that an antibiotic may help, though I’m weary of using them. I think antibiotics are over used and negatively affect the good bacteria that are essential to life.
What caught my eye in this article was that some European nations do not allow the use of biologics, which I assume include Humira & Remicade. Question is, why not? My guess is because they put patients in great risk of getting fatal infections.
November 3, 2010 — An antibiotic currently indicated for hepatic encephalopathy and traveler’s diarrhea has shown promise in the treatment of Crohn’s disease (CD).
RETIC-03, a large phase 2 trial presented at the 18th Annual United European Gastroenterology Week in Barcelona, Spain, showed that rifaximin-EIR (extended intestinal release) was able to achieve clinical remission of Crohn’s sequelae in up to 62% of patients out to 12 weeks, according to study investigator, Herbert Lochs, MD, from the Medical University in Innsbruck, Austria.
Results showed that at 12 weeks, all active treatment groups achieved remission more often than placebo (P < .04), with the highest rate (62.2%) observed for the 800 mg regimen.
Commenting on his motivation for conducting RETIC-03, Dr. Lochs said that he was trying to move away from CD treatment methods that rely on suppression of the patient’s immune system. “It’s not something you ideally want to do — not in the long term.”
In the current hypothesis for the pathogenesis of CD, he explained, there is a change in the intestinal microbiota, whereby pathogenic bacteria disrupt the gut’s mucosa, which activates the immune system. Rather than inhibit the immune response, Dr. Lochs wants to attenuate the reasons for its activation.
The choice of rifaximin was based on case reports of its potential utility in CD, and the fact that it is specific to the gut. “The formulation stays in the lumen; there’s no systemic effect that might lead to overall antibiotic resistance,” said Dr. Lochs. In theory, this should lead to fewer adverse events than other antibiotics, he added.
“The data for antibiotics [in CD] are out there, and the science makes sense,” said Sunanda Kane, MD, from the Mayo Clinic in Rochester, Minnesota, and chair of the Patient Education Committee of the Crohn’s and Colitis Foundation. “The problem up to now has been that no company has wanted to fund a large enough trial with the appropriate antibiotic.”
Dr. Kane said that there is perhaps a different sort of motivation for such a study in the European Union, pointing out that the biologics commonly used in CD are very expensive and often not covered; in some countries, they are not even approved.
“What they are trying to do is to find an alternative to biologics that may be safer and work just as well,” she observed.
Dr. Kane finds the choice of rifaximin in this study to be both prudent and just a bit ironic. “There are case studies that show efficacy, and the fact that it’s so [gastrointestinal]-specific, so targeted, is great, but rifaximin is not a cheap antibiotic.” Still, she admitted, the price is nowhere near that of a biologic, nor does it carry the same potential for serious adverse effects.
Water Therapy – Benefits of Water Therapy [22Jan07]
Nov 2nd
Has anyone with IBD, or IBS tried this? Might be worth a shot.
What is Water Therapy & how to do it?
Early morning, after you get up from bed, (without even brushing your teeth) drink 1.50 liters of water i.e. 5 to 6 glasses. You may wash your face thereafter. This is called water therapy.
Here it is very essential to note that nothing else, neither drinks nor solid food of any sort should be taken within 1 hour before and after drinking these 1.5 liters of water. It is also to be strictly observed that no alcoholic drinks shall be taken the previous night.
If required, boiled and filtered water may be used for this purpose. Is it possible to drink 1.50 liters of water at one time? To begin with, one may find it difficult to drink 1.50 liters of water at one time, but one will get used to it gradually.
Initially, while practicing you may drink four glasses first and then the balance two glasses after a gap of 2 minutes. Initially you may find the necessity to urinate 2-3 times within an hour, but it will become normal after quite some time.
Benefits of Water Therapy
Relief from stress, weight loss, glowing skin, feeling fresh and energetic throughout the day and good digestion are some of the major benefits of
water therapy. Have a look at some of the comments below made by people after trying water therapy.
1. Ever since I started this water therapy, I have noticed a glow on my skin, my eyes sparkle, and I feel so clean and so beautiful. I noticed that I always have a bowel movement after my water therapy and my constipation is gone.
2. Water therapy is just amazing! Though I have to urinate a lot of times in an hour but it makes sense. It makes me feel so good. Thanks to this water therapy. Thank GOD for giving us the water to drink.
3. Water therapy is really wonderfully beneficial. So much that people who have not practiced this can’t even imagine. It makes your body thoroughly clean and pure from inside and outside. I recommend that everybody should start practicing water therapy to keep tremendously fit and disease free.
WANTED: Crohn’s End – 17 Backers on Kickstarter, Please #help us. Thanks! [01Nov10]
Nov 1st
When all else fails, listen to your gut. Every dollar brings us closer toward actualizing this production.
cc @reidkimball (Director)
I have Crohn’s disease.
WANTED: Crohn’s End
documentary about people with Crohn’s disease and Ulcerative Colitis who use alternatives when nothing else is working. They have listened to their gut and took a proactive approach to ending their disease.
- Document stories of triumph over the disease.
- Create more awareness for safer, cheaper, more effective alternative treatments.
- Change how Crohn’s and Colitis are treated by conventional healthcare so we have more cases of triumph than suffering.
- Spark a national movement emphasizing patient’s right to be made aware of and to choose from all available treatments.
Some of these alternatives are controversial and even illegal. For people to receive Helminthic Therapy, they must travel outside of the US because the FDA has not approved them for use and banned the sale of them. Colloidal Silver has the reputation of easily turning people blue, despite this risk being lower than getting into a car accident. THC Oil, which naturally comes from the Marijuana plant is illegal in the US and Canada. Raw milk, another alternative many with Crohn’s have found essential to their health is difficult to get in the US and banned in all of the Canada.
We’ve got a growing fan base on Twitter and Facebook. We seek to continue to grow this community so we can spread awareness about these diseases, alternative treatments and the documentary.
The more we raise together, the better this film will become and ultimately, the more likely people will overcome their Crohn’s disease or Ulcerative Colitis. Not only would your support mean a great deal to me, but it would mean the world to millions of others with these two diseases.
Reid Bryant Kimball
Read more at www.kickstarter.com
Physician William D. Leak was found to have performed unnecessary nerve tests and excessive invasive procedures, including injecting some patients with agents that destroy nerve tissue. But that didn’t stop Eli Lilly from using him as a promotional speaker and adviser.